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Proceedings of the Royal Society of... Sep 1964
Topics: Adenoma; Bone Cysts; Calcium; Calcium, Dietary; Diagnosis, Differential; Ergocalciferols; Humerus; Lactates; Maxilla; Neoplasms; Parathyroid Neoplasms; Pathology; Radiography, Dental; Surgical Procedures, Operative
PubMed: 14208022
DOI: No ID Found -
BMC Musculoskeletal Disorders Nov 2015The efficiency of treating simple bone cyst (SBC) is low. Depending on the choice of treatment, a positive response occurs in 20 to 80 % of cases. These rates are...
BACKGROUND
The efficiency of treating simple bone cyst (SBC) is low. Depending on the choice of treatment, a positive response occurs in 20 to 80 % of cases. These rates are unacceptable, particularly considering they concern the treatment of benign lesions affecting children. Although cyst curettage is one of the first known ways of treating SBC, no precise qualification criteria exists for this procedure. The aim of our study is to identify which type of cyst may be most effectively treated using curettage with grafting.
METHODS
A retrospective analysis was performed on 24 patients referred to our clinic for SBC treatment. To identify predictive factors, the group of patients who positively responded to treatment (Neer stages I and II, n = 14) were compared with the group in which recurrences occurred (Neer stages III and IV, n = 10).
RESULTS
Significantly fewer patients with lesions located in the humerus (chi(2) = 9.351; p < 0.05) and without pathological facture at the time of diagnosis (p = 0.017) were found in the group with no recurrence. The following radiological parameters were found to vary significantly between groups: cyst area (z = 3.121; p < 0.01), cyst index (z = 2.213; p < 0.05) and cyst diameter ratio (z = 2.202; p < 0.05). In the group with no recurrences, the mean values of these parameters were found to be lower than in group with poor response to treatment. No statistically significant differences regarding age, sex or type of bone graft (p > 0.05) were found. Recurrences were experienced by 10 patients (41.7 %) during the 3-year period after surgery
CONCLUSION
In the group treated with curettage, associations were identified between worse treatment results and the location in the humerus, pathological fractures at the time of diagnosis, large cyst area, large cyst index and large cyst diameter.
Topics: Adolescent; Bone Cysts; Bone Transplantation; Child; Curettage; Female; Follow-Up Studies; Humans; Male; Predictive Value of Tests; Radiography; Retrospective Studies; Treatment Outcome
PubMed: 26573858
DOI: 10.1186/s12891-015-0797-6 -
Orthopaedic Surgery Dec 2022Recurrence is the main hinderance in treatment of aneurysmal bone cysts (ABCs). Therefore, several treatment modalities and adjuvant therapies have been proposed. In...
OBJECTIVE
Recurrence is the main hinderance in treatment of aneurysmal bone cysts (ABCs). Therefore, several treatment modalities and adjuvant therapies have been proposed. In this study, we aim to evaluate the long-term effectiveness of percutaneous curettage and allogenic bone grafting as a new, minimally invasive modality in treating ABCs.
METHODS
We performed a retrospective review of the medical records of patients diagnosed with primary ABCs at a university hospital over a 10-year period (2000-2010). We selected all patients who were diagnosed with primary ABC in the extremities and pelvis, treated with the same surgical procedure, and were followed for at least 2 years postoperatively. All patients underwent the same procedure of percutaneous curettage and impaction of allogenic pulverized fine bone fragments (harvested from locally stored femoral heads) mixed with autologous bone marrow aspirate from the iliac bone. We reported patient's characteristics (age and gender), site and size of the lesion, presenting symptoms, Capanna classification, follow-up duration, and post-operative complications. Assessment of cyst healing was based on the appearance on radiographs according to the modified Neer classification.
RESULTS
Nineteen patients were included in this study; 10 patients were males and nine were females. The mean age was 9.6 years (range 3-15). The location of the lesions was as follows: femur (eight), tibia (four), pelvis (four), proximal humerus (one), distal radius (one), and calcaneus (one). The most common presenting symptom was pain in the involved area. Pathological fracture was the presenting feature in two patients. The mean follow-up duration was 6.4 years (range 2-18). The earliest radiological sign of incorporation of the allograft was seen at 3 months after surgery. All patients showed bone remodeling and radiographic resolution (classified as either A or B on the modified Neer classification) of their cystic lesions within 6 months. No local recurrence, infection, or pathological fractures occurred during the follow-up period.
CONCLUSION
Percutaneous curettage and impaction of allogenic bone graft mixed with autogenic bone marrow aspirate is an efficient, minimally invasive, reproducible, and affordable procedure for the treatment of primary ABCs.
Topics: Humans; Child, Preschool; Child; Adolescent; Bone Transplantation; Bone Cysts, Aneurysmal
PubMed: 36250563
DOI: 10.1111/os.13511 -
Journal of Orthopaedic Surgery (Hong... Dec 2015To review the outcome after intralesional curettage without bone grafting for simple bone cysts in the capitate.
PURPOSE
To review the outcome after intralesional curettage without bone grafting for simple bone cysts in the capitate.
METHODS
Records of 12 hands in 10 consecutive females aged 14 to 21 (mean, 17.5) years who underwent intralesional curettage without bone grafting for a simple bone cyst in the capitate were reviewed. Clinical outcome was evaluated using the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire. Wrist/hand pain was assessed using the modified Mayo wrist score. Patient satisfaction, range of motion, and grip strength were self-evaluated as improved, unchanged, or worse.
RESULTS
After a mean follow-up of 7.5 (range, 2.5- 12.5) years, the mean DASH score was 12.3 (range, 0-25), and the mean modified Mayo wrist score was 85 (range, 70-95); the modified Mayo wrist score was excellent in 8 hands and good in 4 hands. All patients had bone union and preservation of capitate height. All patients had no pain except for 2 patients (4 hands) who reported pain after strenuous activity. All patients had improved range of motion, and all but 2 patients had improved grip strength.
CONCLUSION
Curettage without bone grafting for a simple bone cyst in the capitate is a sufficient and viable option.
Topics: Adolescent; Bone Cysts; Bone Transplantation; Capitate Bone; Female; Humans; Orthopedic Procedures; Range of Motion, Articular; Wrist Joint; Young Adult
PubMed: 26715719
DOI: 10.1177/230949901502300322 -
Ear, Nose, & Throat Journal Apr 2023Aneurysmal bone cysts (ABCs) are a rare benign bone lesion, which are divided into primary and secondary categories, and occur mainly in the vertebra and the long... (Review)
Review
INTRODUCTION
Aneurysmal bone cysts (ABCs) are a rare benign bone lesion, which are divided into primary and secondary categories, and occur mainly in the vertebra and the long tubular bones. Primary ABCs in the nasal cavity and the sinuses are rare.
CASE PRESENTATION
We reported on a one-year-old boy who suffered from progressive nasal obstruction and intermittent nosebleeds over a period of approximately 1 month. The patient had no history of trauma or surgery. Physical examination showed a red tumor in his right nasal cavity. A magnetic resonance imaging scan showed a multicystic lesion arising from the ethmoid sinus. The lesion was resected under a nasal endoscope without any complications. Histological evaluation confirmed that the lesion was an aneurysmal bone cyst. Because an osteoma was found during the surgery on the cyst, the lesion was considered secondary clinically. However, fluorescence in situ hybridization testing showed a rearrangement of the USP6 (ubiquitin-specific protease 6) oncogene on chromosome 17. No recurrence was observed after 1 year.
CONCLUSION
An ABC of the nasal cavity and sinuses in such a young child is very rare and needs to be further analyzed according to postoperative pathology and combined with a genetic examination to make a diagnosis. Endoscopic sinus surgery is an effective method of treatment for this kind of disease.
Topics: Male; Humans; Child; Infant; Nasal Cavity; Bone Cysts, Aneurysmal; In Situ Hybridization, Fluorescence; Nose; Nasal Obstruction; Ubiquitin Thiolesterase
PubMed: 35428416
DOI: 10.1177/01455613221081569 -
Acta Orthopaedica Et Traumatologica... Jan 2020The aim of this study was to compare the outcome of intra-lesional autologous bone marrow concentrate (BMC) and equine derived demineralized bone matrix (EDDBM)... (Comparative Study)
Comparative Study
Treatment of simple bone cyst with bone marrow concentrate and equine-derived demineralized bone matrix injection versus methylprednisolone acetate injections: A retrospective comparative study.
OBJECTIVE
The aim of this study was to compare the outcome of intra-lesional autologous bone marrow concentrate (BMC) and equine derived demineralized bone matrix (EDDBM) injections with methylprednisolone acetate injections in patients with simple bone cyst.
METHODS
Clinical records and radiographs of 53 consecutive patients (37 females,and 16 males; mean age: 10.6±1.53 years) treated between 2006 and 2016 were retrospectively reviewed. Healing was assessed by an independent radiologist according to Neer scoring system. Functional outcome was assessed with the Activity Scale for Kids (ASK). Thirty-four cysts were in the humerus, 13 in the femur and 6 in other locations. Twenty-nine patients were included in Steroid Group and treated with 3 cycles of injections of methylprednisolone acetate, while 24 patients were treated with injection of autologous bone marrow concentrate and equine derived demineralized bone matrix (BMC+ EDDBM Group). The two groups were homogenous for the mean age, sex distribution, cysts location and their clinical presentation.
RESULTS
At a minimum follow-up of 24 months, success rate (Neer/Cole score 3 and 4) was higher in EDDBM+BMC group (83.3% vs 58.6%; p=0.047). Female patients had higher healing rates in both groups (p=0.002). No association was found between healing and age (p=0.839), cyst activity (p=0.599), cyst localization (p=0.099) and clinical presentation (p=0.207). BMC+EDDBM group showed higher ASK score (p=0.0007).
CONCLUSION
Treatment with BMC+EDDBM injections may provide better results with a single procedure than 3 methylprednisolone acetate injections and represent an interesting alternative for the treatment of unicameral bone cysts.
LEVEL OF EVIDENCE
Level III, Therapeutic Study.
Topics: Biocompatible Materials; Bone Cysts; Bone Marrow Transplantation; Bone Matrix; Child; Female; Glucocorticoids; Humans; Injections, Intralesional; Male; Methylprednisolone Acetate; Radiography; Retrospective Studies; Treatment Outcome
PubMed: 32175897
DOI: 10.5152/j.aott.2020.01.371 -
Asian Journal of Surgery Oct 2022
Topics: Bone Cysts; Bone Plates; Bone and Bones; Fracture Fixation, Internal; Humans
PubMed: 35513986
DOI: 10.1016/j.asjsur.2022.04.103 -
Journal of Medical Case Reports Sep 2019A traumatic bone cyst is an uncommon nonneoplastic lesion of the jaws that is considered as a "pseudocyst" because of the lack of an epithelial lining. This lesion is... (Review)
Review
BACKGROUND
A traumatic bone cyst is an uncommon nonneoplastic lesion of the jaws that is considered as a "pseudocyst" because of the lack of an epithelial lining. This lesion is particularly asymptomatic and therefore is diagnosed by routine dental radiographic examination as a unilocular radiolucency with scalloped borders, mainly in the posterior mandibular region. The exact etiopathogenesis of the lesion remains uncertain, though it is often associated with trauma.
CASE PRESENTATION
We report three Persian cases of traumatic bone cyst with different clinical and radiographic features, and we present a review of the literature to further discuss diagnostic and treatment challenges. Only one of the three patients reported a history of trauma, and despite the usual signs and symptoms of the lesion, extension of the defect to the ramus, swelling of the lingual cortex, and their unusual presence in the anterior mandible were noted in these patients.
CONCLUSIONS
Because features of this cyst can be varied, careful history taking and radiographic evaluation alongside the clinical signs and symptoms have a very significant role in definitive diagnosis, appropriate treatment, and accurate assessment of prognosis.
Topics: Accidental Falls; Adolescent; Bone Cysts; Cone-Beam Computed Tomography; Female; Humans; Mandibular Diseases; Radiography, Panoramic; Young Adult
PubMed: 31530284
DOI: 10.1186/s13256-019-2220-7 -
European Radiology Experimental Feb 2022Dual-energy computed tomography has shown a great interest for musculoskeletal pathologies. Photon-counting spectral computed tomography (PCSCT) can acquire data in...
BACKGROUND
Dual-energy computed tomography has shown a great interest for musculoskeletal pathologies. Photon-counting spectral computed tomography (PCSCT) can acquire data in multiple energy bins with the potential to increase contrast, especially for soft tissues. Our objectives were to assess the value of PCSST to characterise cartilage and to extract quantitative measures of subchondral bone integrity.
METHODS
Seven excised human knees (3 males and 4 females; 4 normal and 3 with osteoarthritis; age 80.6 ± 14 years, mean ± standard deviation) were scanned using a clinical PCSCT prototype scanner. Tomographic image reconstruction was performed after Compton/photoelectric decomposition. Virtual monoenergetic images were generated from 40 keV to 110 keV every 10 keV (cubic voxel size 250 × 250 × 250 μm). After selecting an optimal virtual monoenergetic image, we analysed the grey level histograms of different tissues and extracted quantitative measurements on bone cysts.
RESULTS
The optimal monoenergetic images were obtained for 60 keV and 70 keV. Visual inspection revealed that these images provide sufficient spatial resolution and soft-tissue contrast to characterise surfaces, disruption, calcification of cartilage, bone osteophytes, and bone cysts. Analysis of attenuation versus energy revealed different energy fingerprint according to tissues. The volumes and numbers of bone cyst were quantified.
CONCLUSIONS
Virtual monoenergetic images may provide direct visualisation of both cartilage and bone details. Thus, unenhanced PCSCT appears to be a new modality for characterising the knee joint with the potential to increase the diagnostic capability of computed tomography for joint diseases and osteoarthritis.
Topics: Aged; Aged, 80 and over; Bone Cysts; Female; Humans; Image Processing, Computer-Assisted; Male; Osteoarthritis, Knee; Tomography, X-Ray Computed
PubMed: 35190914
DOI: 10.1186/s41747-021-00261-x -
Medicina Oral, Patologia Oral Y Cirugia... Sep 2020The aim of this study was to describe the relative frequency and the main demographic and clinic-radiographic features related to patients diagnosed with Simple bone... (Review)
Review
BACKGROUND
The aim of this study was to describe the relative frequency and the main demographic and clinic-radiographic features related to patients diagnosed with Simple bone cyst (SBC) in an Oral Diagnosis Service in Southeast Brazil and present a review and discussion of international literature on this topic.
MATERIAL AND METHODS
SBC cases from our service encompassing the period between 1978 and 2017 were selected. In addition, a literature search was performed in the Pubmed/MEDLINE online electronic database published between 1951 and 2019.
RESULTS
A total of 2,459 cystic lesions were documented in our service, thus 60 patients were diagnosed with the SBC representing 2.4% of all jaw cystic. Most of cases were asymptomatic. Multiple SBC lesions were seen in two patients (3.4%) and association with cemento-osseous dysplasia was seen in one female patient (1.7%). A total of 793 cases were enrolled in this literature review.
CONCLUSIONS
The SBC is an asymptomatic lesion often discovered in routine image exams in young patients. The unilocular, well defined margin with scalloped appearance is characteristic and helps the definition of diagnosis. This review suggests a different epidemiologic trend concerning to the sex and it confirms the posterior region of mandible as the more frequent location. The conservative treatment with limited exploration and curettage remains as the gold-standard treatment.
Topics: Bone Cysts; Brazil; Female; Humans; Mandible; Odontogenic Tumors; Schools
PubMed: 32683391
DOI: 10.4317/medoral.23638